Understanding Pharmacological Effects of Oral Antidiabetic Agents Quiz Test your knowledge on the pharmacological effects and mechanisms of action of oral antidiabetic medications. Learn about common adverse effects, contraindications, and clinical indications.
#1
Which of the following is a common adverse effect of metformin?Hypoglycemia
Weight gain
Lactic acidosis
Hypertension
#2
Which oral antidiabetic agent works primarily by increasing insulin sensitivity in target tissues?Metformin
Sulfonylureas
Thiazolidinediones
Meglitinides
#3
Which oral antidiabetic agent stimulates insulin release from pancreatic beta cells in a glucose-dependent manner?Metformin
Sulfonylureas
Thiazolidinediones
DPP-4 inhibitors
#4
Which class of oral antidiabetic agents inhibits the enzyme dipeptidyl peptidase-4 (DPP-4)?SGLT-2 inhibitors
Meglitinides
DPP-4 inhibitors
Alpha-glucosidase inhibitors
#5
Which oral antidiabetic agent acts by inhibiting the enzyme alpha-glucosidase in the small intestine?Sulfonylureas
Thiazolidinediones
Alpha-glucosidase inhibitors
DPP-4 inhibitors
#6
Which oral antidiabetic agent is associated with an increased risk of urinary tract infections and genital mycotic infections?Sulfonylureas
SGLT-2 inhibitors
Thiazolidinediones
DPP-4 inhibitors
#7
Which of the following is NOT a mechanism of action of SGLT-2 inhibitors?Inhibition of glucose reabsorption in the kidneys
Stimulation of insulin secretion
Promotion of glucosuria
Reduction of plasma glucose levels
#8
Which of the following statements about GLP-1 receptor agonists is true?They promote gluconeogenesis in the liver
They inhibit gastric emptying
They increase insulin resistance
They decrease pancreatic insulin secretion
#9
Which of the following is a contraindication for the use of pioglitazone?Chronic kidney disease
Heart failure
Peripheral neuropathy
Osteoporosis
#10
Which of the following statements about repaglinide is correct?It belongs to the class of biguanides
It has a longer duration of action compared to other meglitinides
It is taken once daily before breakfast
It stimulates insulin secretion in a glucose-independent manner
#11
Which of the following is NOT a common adverse effect of thiazolidinediones?Weight gain
Hypoglycemia
Edema
Increased risk of fractures
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