Retroviral Biology Quiz

Test your knowledge on retroviruses with questions on reverse transcription, target cells, gene functions, diseases, and antiretroviral drugs.

#1

Which enzyme is responsible for the reverse transcription of retroviral RNA into DNA?

RNA polymerase
DNA ligase
Reverse transcriptase
DNA polymerase
#2

What is the primary target cell type for HIV infection?

T lymphocytes
B lymphocytes
Macrophages
Neutrophils
#3

Which retrovirus is associated with the development of adult T-cell leukemia?

HIV-1
HIV-2
HTLV-1
HTLV-2
#4

What is the role of the env gene in retroviruses?

Encodes reverse transcriptase
Promotes integration into host genome
Codes for envelope proteins
Induces cell lysis
#5

What is the mechanism of retroviral entry into host cells?

Endocytosis
Direct fusion with the plasma membrane
Phagocytosis
Exocytosis
#6

Which retrovirus is associated with causing a type of cancer known as Kaposi's sarcoma?

HIV-1
HIV-2
HTLV-1
HHV-8
#7

Which retroviral protein facilitates the integration of the viral DNA into the host genome?

Reverse transcriptase
Integrase
Protease
Capsid protein
#8

Which retrovirus is associated with causing leukemia in animals?

HIV
HTLV
HERV
MLV
#9

What is the function of the gag gene in retroviruses?

Encodes reverse transcriptase
Capsid protein synthesis
Promotes integration into host genome
Induces cell lysis
#10

Which retrovirus is associated with causing immunodeficiency in non-human primates?

HIV-1
HIV-2
SIV
FIV
#11

What is the significance of the pol gene in retroviruses?

Encodes capsid protein
Synthesizes envelope proteins
Codes for reverse transcriptase and integrase
Promotes integration into host genome
#12

Which type of retrovirus is known to be endogenous and inherited in the germ line of some species?

HTLV
HERV
MLV
FIV
#13

What is the main function of the RRE (Rev-responsive element) in retroviral RNA?

Enhances reverse transcription
Promotes translation of viral proteins
Regulates RNA export from the nucleus
Induces apoptosis
#14

In retroviral replication, what is the function of the protease enzyme?

Cleaves viral RNA into individual nucleotides
Cleaves viral proteins into functional units
Promotes integration into the host genome
Initiates reverse transcription

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