#1
Which gene mutation is primarily responsible for cystic fibrosis?
CFTR gene
BRCA1 gene
TP53 gene
EGFR gene
#2
What is the most common symptom of cystic fibrosis?
Chronic cough
Salty-tasting skin
Shortness of breath
Frequent lung infections
#3
What is the mode of inheritance of cystic fibrosis?
X-linked recessive
Autosomal dominant
Autosomal recessive
Y-linked
#4
Which diagnostic test is commonly used to confirm cystic fibrosis?
Complete blood count (CBC)
Electrocardiogram (ECG)
Sweat chloride test
Chest X-ray
#5
What is the average life expectancy for individuals with cystic fibrosis?
20-30 years
40-50 years
60-70 years
80-90 years
#6
What is the main cause of pancreatic insufficiency in cystic fibrosis?
Obstruction of pancreatic ducts by mucus
Genetic mutation in pancreatic cells
Autoimmune destruction of pancreatic tissue
Excessive production of digestive enzymes
#7
Which of the following is NOT a potential complication of cystic fibrosis?
Liver disease
Osteoporosis
Type 1 diabetes
Hearing loss
#8
Which of the following is a treatment option for cystic fibrosis?
Anticoagulant therapy
Insulin injections
Bronchodilator medications
Antidepressant drugs
#9
Which of the following is NOT a characteristic feature of cystic fibrosis?
Salty-tasting skin
Meconium ileus
Hypertension
Chronic sinusitis
#10
Which of the following is a common respiratory manifestation of cystic fibrosis?
Emphysema
Pulmonary fibrosis
Bronchiectasis
Pleural effusion
#11
Which of the following is a potential gastrointestinal complication of cystic fibrosis?
Cholecystitis
Pancreatitis
Gastric ulcer
Malabsorption
#12
Which ethnic group has the highest incidence of cystic fibrosis?
Caucasians
African Americans
Hispanics
Asians
#13
What is the primary cause of death in individuals with cystic fibrosis?
Respiratory failure
Heart disease
Liver failure
Kidney failure
#14
What is the hallmark respiratory manifestation of cystic fibrosis?
Chronic obstructive pulmonary disease (COPD)
Asthma
Bronchiolitis obliterans
Pulmonary hypertension
#15
Which of the following is a potential complication of cystic fibrosis-related diabetes?
Hypoglycemia
Hypercalcemia
Hypotension
Hypothyroidism
#16
What is the role of the CFTR protein in the body?
Regulates sodium absorption
Promotes mucus production
Inhibits enzyme secretion
Controls insulin release
#17
Which of the following is a common respiratory complication of cystic fibrosis in infants?
Pulmonary embolism
Meconium ileus
Pneumothorax
Acute respiratory distress syndrome (ARDS)
#18
Which organ systems are primarily affected by cystic fibrosis?
Respiratory and gastrointestinal systems
Cardiovascular and nervous systems
Muscular and skeletal systems
Endocrine and reproductive systems
#19
How does cystic fibrosis affect fertility in males?
Increases sperm production
Blocks the vas deferens
Causes erectile dysfunction
Reduces testosterone levels
#20
What is the gold standard method for diagnosing cystic fibrosis?
Genetic testing
Sweat chloride test
Chest X-ray
Pulmonary function test
#21
What is the primary defect in cystic fibrosis?
Defective mucus production
Abnormal lung development
Impaired ciliary function
Dysfunctional immune response
#22
Which of the following organs is NOT affected by cystic fibrosis?
Lungs
Liver
Kidneys
Pancreas
#23
Which of the following is NOT a symptom of cystic fibrosis-related liver disease?
Jaundice
Ascites
Frequent urination
Fatigue
#24
How does cystic fibrosis affect the viscosity of mucus?
Increases mucus viscosity
Decreases mucus viscosity
Has no effect on mucus viscosity
Converts mucus into water
#25
What is the recommended treatment for meconium ileus in newborns with cystic fibrosis?
Oral laxatives
Surgical intervention
Antibiotics
Inhaled corticosteroids