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Cystic Fibrosis: Diagnosis, Clinical Manifestations, Genetic Basis, and Complications Quiz

#1

Which gene mutation is primarily responsible for cystic fibrosis?

CFTR gene
Explanation

Mutation in CFTR gene leads to dysfunctional chloride channels.

#2

What is the most common symptom of cystic fibrosis?

Salty-tasting skin
Explanation

Due to high salt concentration in sweat.

#3

What is the mode of inheritance of cystic fibrosis?

Autosomal recessive
Explanation

Both parents must carry the faulty gene.

#4

Which diagnostic test is commonly used to confirm cystic fibrosis?

Sweat chloride test
Explanation

Elevated chloride levels indicate the presence of cystic fibrosis.

#5

What is the average life expectancy for individuals with cystic fibrosis?

40-50 years
Explanation

Advancements in treatment have increased life expectancy.

#6

What is the main cause of pancreatic insufficiency in cystic fibrosis?

Obstruction of pancreatic ducts by mucus
Explanation

Mucus blocks pancreatic enzymes from reaching the intestines.

#7

Which of the following is NOT a potential complication of cystic fibrosis?

Type 1 diabetes
Explanation

CF is not directly linked to Type 1 diabetes.

#8

Which of the following is a treatment option for cystic fibrosis?

Bronchodilator medications
Explanation

Helps to widen airways and ease breathing.

#9

Which of the following is NOT a characteristic feature of cystic fibrosis?

Hypertension
Explanation

Hypertension is not typically associated with CF.

#10

Which organ systems are primarily affected by cystic fibrosis?

Respiratory and gastrointestinal systems
Explanation

CF affects primarily the lungs and digestive system.

#11

How does cystic fibrosis affect fertility in males?

Blocks the vas deferens
Explanation

Caused by thickening of seminal fluid.

#12

What is the gold standard method for diagnosing cystic fibrosis?

Genetic testing
Explanation

Identifies specific mutations in CFTR gene.

#13

What is the primary defect in cystic fibrosis?

Defective mucus production
Explanation

Results in thick, sticky mucus.

#14

Which of the following organs is NOT affected by cystic fibrosis?

Kidneys
Explanation

Kidneys are not typically affected.

#15

Which of the following is NOT a symptom of cystic fibrosis-related liver disease?

Frequent urination
Explanation

Frequent urination is not a common symptom.

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