Principles of Instrumental Analysis in Mass Spectrometry Quiz

Test your knowledge on mass spectrometry principles with questions covering ionization, analyzers, and applications.

#1

What is the primary function of the ionization source in mass spectrometry?

To generate ions from sample molecules
To detect ions
To analyze ion masses
To separate ions based on their mass-to-charge ratio
#2

Which component in mass spectrometry separates ions based on their mass-to-charge ratio?

Analyzer
Detector
Ionization source
Vacuum system
#3

In mass spectrometry, what is the purpose of the detector?

To generate ions from the sample
To separate ions based on their mass-to-charge ratio
To detect ions and measure their abundance
To analyze ion masses
#4

Which mass spectrometry technique is commonly used for the analysis of volatile organic compounds (VOCs)?

Matrix-Assisted Laser Desorption/Ionization (MALDI)
Gas Chromatography-Mass Spectrometry (GC-MS)
Liquid Chromatography-Mass Spectrometry (LC-MS)
Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR MS)
#5

Which of the following is an advantage of electrospray ionization (ESI) in mass spectrometry?

Low sensitivity
Limited sample types
High sensitivity and compatibility with biomolecules
Fast analysis time
#6

In mass spectrometry, what does the term 'm/z' represent?

Mass-to-charge ratio of ions
Total mass of the sample
Ionization potential
Detector sensitivity
#7

Which type of mass spectrometry provides information about the structure of molecules?

Time-of-Flight (TOF)
Quadrupole
Tandem Mass Spectrometry (MS/MS)
Electrospray Ionization (ESI)
#8

What is the purpose of a collision cell in tandem mass spectrometry?

To separate ions based on their mass-to-charge ratio
To detect ions
To induce collisions and fragment ions
To analyze ion masses
#9

Which ionization technique is commonly used in proteomics for analyzing large biomolecules such as proteins?

Electron Impact Ionization (EI)
Chemical Ionization (CI)
Matrix-Assisted Laser Desorption/Ionization (MALDI)
Electrospray Ionization (ESI)
#10

Which type of mass spectrometry is particularly useful for analyzing the isotopic composition of elements?

Quadrupole
Magnetic Sector
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
Time-of-Flight (TOF)
#11

Which of the following is a soft ionization technique used in mass spectrometry?

Electron Impact Ionization (EI)
Chemical Ionization (CI)
Fast Atom Bombardment (FAB)
Glow Discharge Ionization (GDI)

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