#1
What is the main focus of the movie 'Lorenzo's Oil'?
A love story
A legal battle
A medical discovery
A political scandal
#2
Which disease does 'Lorenzo's Oil' primarily address?
Cystic fibrosis
Adrenoleukodystrophy (ALD)
Huntington's disease
Parkinson's disease
#3
In which year was the movie 'Lorenzo's Oil' released?
#4
Who are the main characters in 'Lorenzo's Oil'?
John and Jane
Lorenzo and his parents
Tom and Sarah
Michael and Emily
#5
What is the purpose of Lorenzo's Oil?
To treat cancer
To cure Alzheimer's disease
To slow the progression of ALD
To prevent heart disease
#6
Who directed the film 'Lorenzo's Oil'?
Steven Spielberg
George Lucas
Francis Ford Coppola
George Miller
#7
What is the typical age of onset for symptoms of ALD in affected males?
Infancy
Early childhood
Adolescence
Adulthood
#8
What is the typical progression of symptoms in ALD?
Motor dysfunction followed by cognitive decline
Cognitive decline followed by motor dysfunction
Speech impairment followed by vision loss
Vision loss followed by speech impairment
#9
Which of the following is NOT a form of ALD?
Childhood cerebral ALD
Adolescent-onset ALD
Adult-onset ALD
Neonatal ALD
#10
What is the prognosis for individuals with ALD?
There is no cure and most affected individuals die within a few years of symptom onset
With early detection and treatment, individuals can have a normal lifespan
Symptoms can be managed, but the disease is usually fatal
Affected individuals typically experience remission after a few years
#11
Which part of the body does Adrenoleukodystrophy (ALD) primarily affect?
The kidneys
The liver
The brain and nervous system
The heart
#12
What is the chemical name of the oil developed in 'Lorenzo's Oil'?
Oleic acid
Erucic acid
Lorenzoic acid
Adrenic acid
#13
What is the inheritance pattern of Adrenoleukodystrophy (ALD)?
Autosomal dominant
X-linked recessive
Autosomal recessive
Y-linked
#14
Which fatty acids are primarily affected in Adrenoleukodystrophy (ALD)?
Saturated fatty acids
Polyunsaturated fatty acids
Monounsaturated fatty acids
Very long-chain fatty acids
#15
Which organelle is primarily affected in cells due to ALD?
Mitochondria
Lysosome
Peroxisome
Endoplasmic reticulum
#16
Which of the following is NOT a treatment approach for ALD?
Dietary modification
Bone marrow transplantation
Gene therapy
Antibiotic therapy
#17
What is the role of VLCFAs (Very Long-Chain Fatty Acids) in the pathogenesis of ALD?
They accumulate in the body and cause toxicity
They are essential for normal cellular function
They help in the breakdown of toxic substances
They regulate gene expression