#1
What is the main focus of the movie 'Lorenzo's Oil'?
A medical discovery
ExplanationThe movie revolves around the discovery of a potential treatment for Adrenoleukodystrophy (ALD).
#2
Which disease does 'Lorenzo's Oil' primarily address?
Adrenoleukodystrophy (ALD)
ExplanationThe film focuses on the genetic disorder ALD and efforts to find a cure for it.
#3
In which year was the movie 'Lorenzo's Oil' released?
1992
ExplanationThe movie 'Lorenzo's Oil' was released in 1992.
#4
Who are the main characters in 'Lorenzo's Oil'?
Lorenzo and his parents
ExplanationThe central characters are Lorenzo, a boy diagnosed with ALD, and his parents, Augusto and Michaela Odone.
#5
What is the purpose of Lorenzo's Oil?
To slow the progression of ALD
ExplanationLorenzo's Oil is developed to slow down the progression of the debilitating effects of Adrenoleukodystrophy.
#6
Who directed the film 'Lorenzo's Oil'?
George Miller
ExplanationThe movie 'Lorenzo's Oil' was directed by George Miller.
#7
What is the typical age of onset for symptoms of ALD in affected males?
Early childhood
ExplanationSymptoms of ALD typically manifest in affected males during early childhood.
#8
What is the typical progression of symptoms in ALD?
Motor dysfunction followed by cognitive decline
ExplanationALD symptoms typically progress from motor dysfunction to cognitive decline.
#9
Which of the following is NOT a form of ALD?
Adolescent-onset ALD
ExplanationAdolescent-onset ALD is not a recognized form of the disease.
#10
What is the prognosis for individuals with ALD?
Symptoms can be managed, but the disease is usually fatal
ExplanationWhile symptoms can be managed, ALD is typically fatal.
#11
Which part of the body does Adrenoleukodystrophy (ALD) primarily affect?
The brain and nervous system
ExplanationALD primarily impacts the brain and nervous system, leading to neurological deterioration.
#12
What is the chemical name of the oil developed in 'Lorenzo's Oil'?
Erucic acid
ExplanationThe oil developed in the movie is named Lorenzo's Oil, and its active component is Erucic acid.
#13
What is the inheritance pattern of Adrenoleukodystrophy (ALD)?
X-linked recessive
ExplanationALD follows an X-linked recessive inheritance pattern, affecting males more severely.
#14
Which fatty acids are primarily affected in Adrenoleukodystrophy (ALD)?
Very long-chain fatty acids
ExplanationALD leads to the accumulation of Very Long-Chain Fatty Acids (VLCFAs) in the body.
#15
Which organelle is primarily affected in cells due to ALD?
Peroxisome
ExplanationALD primarily affects the peroxisomes in cells.
#16
Which of the following is NOT a treatment approach for ALD?
Antibiotic therapy
ExplanationAntibiotic therapy is not a recognized treatment for ALD.
#17
What is the role of VLCFAs (Very Long-Chain Fatty Acids) in the pathogenesis of ALD?
They accumulate in the body and cause toxicity
ExplanationAccumulation of VLCFAs in the body due to ALD causes toxicity.