Immune System and Transplant Immunology Quiz

Explore key concepts in transplant immunology with these challenging questions. From antibody production to graft rejection mechanisms, assess your understanding now!

#1

Which cells are primarily responsible for antibody production?

T cells
B cells
Natural killer cells
Macrophages
#2

What is the role of dendritic cells in the immune system?

Produce antibodies
Destroy infected cells
Present antigens to T cells
Produce cytokines
#3

Which type of immune response is primarily involved in defending against intracellular pathogens such as viruses?

Humoral immunity
Cell-mediated immunity
Innate immunity
Passive immunity
#4

What is the main function of cytotoxic T cells?

Produce antibodies
Destroy infected cells
Present antigens to B cells
Produce cytokines
#5

Which cells are responsible for antigen presentation to T cells in the context of transplantation?

B cells
Macrophages
Dendritic cells
Natural killer cells
#6

Which of the following is a major histocompatibility complex (MHC) class II molecule?

HLA-A
HLA-B
HLA-C
HLA-D
#7

Which immunosuppressive drug inhibits T cell activation by blocking the IL-2 receptor?

Cyclosporine
Tacrolimus
Mycophenolate mofetil
Basiliximab
#8

Which type of graft involves transferring tissue or organs between genetically identical individuals?

Autograft
Allograft
Xenograft
Syngeneic graft
#9

Which cytokine is primarily responsible for promoting the differentiation of B cells into plasma cells?

Interferon-gamma
Interleukin-2
Interleukin-4
Tumor necrosis factor-alpha
#10

What is the primary target of immunosuppressive drugs in transplant patients?

B cells
T cells
Macrophages
Natural killer cells
#11

What is graft-versus-host disease (GVHD) in the context of transplantation?

Donor T cells attack the recipient's tissues
Recipient antibodies attack the donor graft
A type of rejection reaction
Complication of immunosuppressive therapy
#12

What is the mechanism of action of monoclonal antibodies used in transplant immunology to prevent rejection?

Blocking T cell activation
Inducing apoptosis of T cells
Inhibiting cytokine production
Depleting B cells
#13

What is the main function of regulatory T cells (Tregs) in transplant immunology?

Promote inflammation and tissue damage
Suppress immune responses and prevent graft rejection
Activate B cells
Differentiate into cytotoxic T cells
#14

What is the role of complement proteins in the immune response to transplantation?

Phagocytosis of pathogens
Activation of T cells
Opsonization of antigens
Lysis of target cells
#15

What is the mechanism of action of rituximab, a monoclonal antibody used in transplant immunology?

Blocking T cell activation
Inducing apoptosis of T cells
Inhibiting cytokine production
Depleting B cells

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