Immune System and Transplant Immunology Quiz

B cells are lymphocytes that produce antibodies, crucial for humoral immunity.

Dendritic cells are antigen-presenting cells that activate T cells by presenting antigens.

Cell-mediated immunity involves T cells directly targeting and destroying infected cells, vital in combating intracellular pathogens.

Cytotoxic T cells recognize and eliminate virus-infected or abnormal cells through inducing apoptosis.

Dendritic cells capture and present antigens to T cells, initiating the adaptive immune response and facilitating transplant rejection or acceptance.

HLA-D is a type of MHC class II molecule involved in presenting antigens to CD4+ T cells.

Cyclosporine inhibits T cell activation by blocking IL-2 production, a crucial cytokine for T cell proliferation.

Syngeneic grafts are transplants between genetically identical individuals, minimizing rejection risk due to genetic compatibility.

Interleukin-4 is a key cytokine driving the differentiation of B cells into plasma cells, which produce antibodies.

Immunosuppressive drugs primarily target T cells to prevent graft rejection by suppressing the immune response.

GVHD occurs when donor T cells recognize recipient tissues as foreign and mount an immune response against them.

Monoclonal antibodies prevent graft rejection by blocking T cell activation, crucial for the immune response against the graft.

Tregs play a crucial role in transplant immunology by suppressing immune responses against the graft, promoting tolerance, and preventing rejection.

Complement proteins can lyse target cells directly, contributing to graft rejection in transplantation.

Rituximab targets CD20 on B cells, leading to their depletion and reducing the risk of antibody-mediated rejection in transplantation.