Factors influencing drug absorption and metabolism Quiz

Test your knowledge on factors influencing drug absorption, metabolism, routes, and organs involved. Get ready for pharmacokinetics!

#1

Which of the following factors can influence drug absorption?

pH of the gastrointestinal tract
Lipid solubility of the drug
Presence of food in the stomach
All of the above
#2

Which organ is primarily responsible for drug metabolism?

Liver
Kidneys
Lungs
Heart
#3

Which of the following is a mechanism by which drugs can be excreted from the body?

Glomerular filtration
Diffusion
Active transport
All of the above
1 answered
#4

What effect does decreased blood flow to the gastrointestinal tract have on drug absorption?

Increases absorption
Decreases absorption
No effect on absorption
May increase or decrease absorption depending on the drug
#5

Which of the following factors can affect drug absorption through the skin?

Skin thickness
Skin hydration
Presence of hair follicles
All of the above
#6

Which of the following is NOT a route of drug excretion?

Renal
Biliary
Pulmonary
Dermal
#7

Which enzyme is involved in the metabolism of many drugs and is particularly abundant in the liver?

Amylase
Lipase
Cytochrome P450
Peptidase
#8

Which route of administration generally results in the fastest drug absorption?

Oral
Intravenous
Subcutaneous
Topical
#9

Which of the following factors is likely to affect drug metabolism in the elderly?

Increased liver enzyme activity
Decreased liver size
Decreased blood flow to the liver
All of the above
#10

Which drug property is particularly important for transdermal drug delivery?

High lipid solubility
Low molecular weight
High water solubility
High protein binding
#11

Which drug characteristic is important for determining its distribution within the body?

Molecular weight
Lipid solubility
Protein binding
All of the above
#12

What is the primary site of drug excretion for drugs that undergo biliary excretion?

Kidneys
Liver
Lungs
Intestines
#13

Which of the following factors is NOT a consideration in drug bioavailability?

First-pass metabolism
Chemical stability of the drug
Drug formulation
Route of administration
#14

What is the term for the process by which a drug moves from the site of administration into the systemic circulation?

Distribution
Absorption
Metabolism
Excretion
#15

Which of the following factors is NOT typically considered in pharmacokinetic modeling?

Drug interactions
Disease states
Patient age
Drug efficacy
#16

Which of the following enzymes is primarily responsible for drug metabolism in the liver?

Glucokinase
Alcohol dehydrogenase
Cytochrome P450
Lactase
#17

Which of the following drug properties is important for determining its renal excretion?

Molecular weight
Lipid solubility
Protein binding
Ionization

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