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Factors influencing drug absorption and metabolism Quiz

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Which of the following factors can influence drug absorption?

All of the above

Explanation

Various factors such as pH, surface area, and blood flow.

Which organ is primarily responsible for drug metabolism?

Liver

Explanation

Liver is the primary site for enzymatic breakdown of drugs.

Which of the following is a mechanism by which drugs can be excreted from the body?

All of the above

Explanation

Excretion occurs via urine, bile, and sweat.

What effect does decreased blood flow to the gastrointestinal tract have on drug absorption?

Decreases absorption

Explanation

Reduced blood flow means less opportunity for absorption into systemic circulation.

Which of the following factors can affect drug absorption through the skin?

All of the above

Explanation

Factors include skin thickness, hydration, and blood flow.

Which of the following is NOT a route of drug excretion?

Dermal

Explanation

Skin is a route of absorption, not excretion.

Which enzyme is involved in the metabolism of many drugs and is particularly abundant in the liver?

Cytochrome P450

Explanation

Cytochrome P450 enzymes play a significant role in drug metabolism.

Which route of administration generally results in the fastest drug absorption?

Intravenous

Explanation

Directly into the bloodstream, bypassing absorption barriers.

Which of the following factors is likely to affect drug metabolism in the elderly?

All of the above

Explanation

Age-related changes impact enzyme activity and organ function.

#10

Which drug property is particularly important for transdermal drug delivery?

High lipid solubility

Explanation

Enhances penetration through skin layers.

#11

Which drug characteristic is important for determining its distribution within the body?

All of the above

Explanation

Factors include size, lipid solubility, and protein binding.

#12

What is the primary site of drug excretion for drugs that undergo biliary excretion?

Intestines

Explanation

Excreted via bile into the intestines.

#13

Which of the following factors is NOT a consideration in drug bioavailability?

Chemical stability of the drug

Explanation

Bioavailability focuses on absorption and availability in systemic circulation.

#14

What is the term for the process by which a drug moves from the site of administration into the systemic circulation?

Absorption

Explanation

Movement from administration site into bloodstream.

#15

Which of the following factors is NOT typically considered in pharmacokinetic modeling?

Drug efficacy

Explanation

Pharmacokinetic models focus on absorption, distribution, metabolism, and excretion.

#16

Which of the following enzymes is primarily responsible for drug metabolism in the liver?

Cytochrome P450

Explanation

Predominantly involved in hepatic drug metabolism.

#17

Which of the following drug properties is important for determining its renal excretion?

Ionization

Explanation

Affects ability to be filtered at the renal tubules.

Factors influencing drug absorption and metabolism Quiz

Which of the following factors can influence drug absorption?

Which organ is primarily responsible for drug metabolism?

Which of the following is a mechanism by which drugs can be excreted from the body?

What effect does decreased blood flow to the gastrointestinal tract have on drug absorption?

Which of the following factors can affect drug absorption through the skin?

Which of the following is NOT a route of drug excretion?

Which enzyme is involved in the metabolism of many drugs and is particularly abundant in the liver?

Which route of administration generally results in the fastest drug absorption?

Which of the following factors is likely to affect drug metabolism in the elderly?

Which drug property is particularly important for transdermal drug delivery?

Which drug characteristic is important for determining its distribution within the body?

What is the primary site of drug excretion for drugs that undergo biliary excretion?

Which of the following factors is NOT a consideration in drug bioavailability?

What is the term for the process by which a drug moves from the site of administration into the systemic circulation?

Which of the following factors is NOT typically considered in pharmacokinetic modeling?

Which of the following enzymes is primarily responsible for drug metabolism in the liver?

Which of the following drug properties is important for determining its renal excretion?

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