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Viral Replication and Pathogenesis Quiz

#1

Which of the following is NOT a step in the viral replication cycle?

Reversal
Explanation

Reversal is not a step in the viral replication cycle.

#2

Which viral family does HIV belong to?

Retroviridae
Explanation

HIV belongs to the Retroviridae viral family.

#3

What is the primary function of viral envelope proteins?

Facilitate attachment to host cells
Explanation

Viral envelope proteins primarily facilitate attachment to host cells.

#4

Which step of the viral replication cycle involves the assembly of viral components into new virions?

Assembly
Explanation

Assembly involves the assembly of viral components into new virions during the viral replication cycle.

#5

What is the term for viruses that contain an envelope composed of host cell membrane and viral proteins?

Enveloped viruses
Explanation

Enveloped viruses contain an envelope composed of host cell membrane and viral proteins.

#6

Which type of viral RNA serves directly as a template for protein synthesis?

Messenger RNA
Explanation

Messenger RNA serves directly as a template for protein synthesis.

#7

Which enzyme is responsible for the synthesis of a complementary RNA strand from a DNA template during viral replication?

RNA polymerase
Explanation

RNA polymerase synthesizes RNA from a DNA template during viral replication.

#8

Which type of viral genome is directly infectious upon entering the host cell?

Positive-sense single-stranded RNA
Explanation

Positive-sense single-stranded RNA genomes are directly infectious upon entering the host cell.

#9

Which viral enzyme is responsible for integrating the viral DNA into the host cell genome?

Integrase
Explanation

Integrase is the viral enzyme responsible for integrating viral DNA into the host cell genome.

#10

Which of the following is NOT a type of viral entry mechanism?

Reverse transcription
Explanation

Reverse transcription is not a type of viral entry mechanism.

#11

Which host cell component is often hijacked by viruses to translate viral proteins?

Ribosomes
Explanation

Viruses often hijack ribosomes to translate viral proteins.

#12

Which type of viral genome requires a viral RNA polymerase for transcription?

Negative-sense single-stranded RNA
Explanation

Negative-sense single-stranded RNA genomes require a viral RNA polymerase for transcription.

#13

Which of the following is NOT a mechanism of viral pathogenesis?

Blockage of viral entry
Explanation

Blockage of viral entry is not a mechanism of viral pathogenesis.

#14

What is the term for viruses that have both RNA and DNA in their life cycle?

Ambisense viruses
Explanation

Ambisense viruses have both RNA and DNA in their life cycle.

#15

Which cellular process is often disrupted by viral proteins to evade host immune response?

Apoptosis
Explanation

Viral proteins often disrupt apoptosis to evade host immune response.

#16

Which of the following is a common mechanism by which viruses evade host immune response?

Antigenic variation
Explanation

Antigenic variation is a common mechanism by which viruses evade host immune response.

#17

Which of the following is NOT a mechanism by which viruses cause disease?

Enhancement of cellular respiration
Explanation

Enhancement of cellular respiration is not a mechanism by which viruses cause disease.

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