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Critical Care Pharmacotherapy and Pain Management in the Intensive Care Unit (ICU) Quiz

#1

Which of the following medications is commonly used for sedation in the ICU?

Lorazepam
Explanation

Benzodiazepine with sedative properties.

#2

What is the primary mechanism of action of opioids in pain management?

Activating opioid receptors
Explanation

Binds to opioid receptors to modulate pain perception.

#3

Which of the following medications is a common choice for treating neuropathic pain in the ICU?

Gabapentin
Explanation

Antiepileptic agent with neuropathic pain relief properties.

#4

What is the preferred route of administration for rapid pain relief in a critically ill patient?

Intravenous
Explanation

Direct administration into the bloodstream for quick effect.

#5

Which of the following medications is a selective serotonin reuptake inhibitor (SSRI) commonly used for treating depression in critically ill patients?

Fluoxetine
Explanation

SSRI with antidepressant effects.

#6

Which of the following is an adverse effect associated with long-term use of opioids in ICU patients?

Respiratory depression
Explanation

Depression of respiratory function due to opioid effects on the brainstem.

#7

Which of the following medications is commonly used for neuromuscular blockade in the ICU?

Vecuronium
Explanation

Non-depolarizing neuromuscular blocking agent.

#8

What is the primary pharmacological action of dexmedetomidine in the ICU?

Analgesia and sedation
Explanation

Provides pain relief and sedation through alpha-2 adrenergic agonism.

#9

What is the mechanism of action of acetaminophen (paracetamol) in pain management?

Reduction of prostaglandin synthesis
Explanation

Inhibits prostaglandin synthesis in the CNS and peripheral tissues.

#10

Which of the following is a potential complication of prolonged use of benzodiazepines for sedation in the ICU?

Seizures
Explanation

Increased risk of epileptic seizures with prolonged benzodiazepine use.

#11

What is the primary mechanism of action of nonsteroidal anti-inflammatory drugs (NSAIDs) in pain management?

Inhibition of prostaglandin synthesis
Explanation

Blocks COX enzymes to inhibit prostaglandin synthesis, reducing pain and inflammation.

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