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Creutzfeldt-Jakob Disease Quiz

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Which of the following is a characteristic feature of Creutzfeldt-Jakob Disease (CJD)?

Progressive memory loss

Explanation

Common initial symptom in CJD.

What is the usual age range for onset of symptoms in sporadic Creutzfeldt-Jakob Disease (sCJD)?

60s to 70s

Explanation

Typical age range for sCJD onset.

Which of the following is NOT a variant of Creutzfeldt-Jakob Disease?

Endemic CJD

Explanation

Not a recognized variant of CJD.

What is the average duration of illness from onset to death in sporadic Creutzfeldt-Jakob Disease?

6-12 months

Explanation

Typical duration of sCJD illness.

Which of the following is a clinical manifestation commonly seen in Creutzfeldt-Jakob Disease?

Myoclonus

Explanation

Involuntary muscle jerks often present.

Which of the following is a variant form of Creutzfeldt-Jakob Disease linked to consumption of contaminated beef?

Bovine spongiform encephalopathy (BSE)

Explanation

BSE-contaminated beef implicated in vCJD.

Which protein plays a central role in the pathogenesis of Creutzfeldt-Jakob Disease?

Prion

Explanation

Prion misfolding leads to CJD.

What is the most common route of transmission for variant Creutzfeldt-Jakob Disease (vCJD)?

Consumption of contaminated beef

Explanation

Linked to BSE-contaminated beef consumption.

Which region of the brain is most severely affected in Creutzfeldt-Jakob Disease?

Frontal lobe

Explanation

Common site of brain degeneration in CJD.

#10

What is the mainstay of treatment for Creutzfeldt-Jakob Disease?

Supportive care

Explanation

No cure; treatment aims at symptom management.

#11

Which of the following is NOT a potential mode of transmission for Creutzfeldt-Jakob Disease?

Droplet inhalation

Explanation

Not known to transmit via droplets.

#12

What is the primary feature of Creutzfeldt-Jakob Disease on MRI scans?

Cortical ribboning

Explanation

Distinctive MRI pattern in CJD.

#13

Which diagnostic test is typically used to confirm Creutzfeldt-Jakob Disease?

Brain biopsy

Explanation

Definitive diagnostic method for CJD.

#14

Which of the following is a potential risk factor for sporadic Creutzfeldt-Jakob Disease?

Genetic mutations

Explanation

Genetic predisposition can increase risk.

#15

Which of the following is a characteristic histopathological finding in Creutzfeldt-Jakob Disease?

Prion protein aggregates

Explanation

Pathological hallmark of CJD.

#16

What is the estimated annual incidence rate of sporadic Creutzfeldt-Jakob Disease per million population?

5-7 cases

Explanation

Incidence rate of sCJD per million.

#17

Which region of the world has reported the highest incidence of variant Creutzfeldt-Jakob Disease cases?

Europe

Explanation

Epidemiologically linked to Europe.

Creutzfeldt-Jakob Disease Quiz

Which of the following is a characteristic feature of Creutzfeldt-Jakob Disease (CJD)?

What is the usual age range for onset of symptoms in sporadic Creutzfeldt-Jakob Disease (sCJD)?

Which of the following is NOT a variant of Creutzfeldt-Jakob Disease?

What is the average duration of illness from onset to death in sporadic Creutzfeldt-Jakob Disease?

Which of the following is a clinical manifestation commonly seen in Creutzfeldt-Jakob Disease?

Which of the following is a variant form of Creutzfeldt-Jakob Disease linked to consumption of contaminated beef?

Which protein plays a central role in the pathogenesis of Creutzfeldt-Jakob Disease?

What is the most common route of transmission for variant Creutzfeldt-Jakob Disease (vCJD)?

Which region of the brain is most severely affected in Creutzfeldt-Jakob Disease?

What is the mainstay of treatment for Creutzfeldt-Jakob Disease?

Which of the following is NOT a potential mode of transmission for Creutzfeldt-Jakob Disease?

What is the primary feature of Creutzfeldt-Jakob Disease on MRI scans?

Which diagnostic test is typically used to confirm Creutzfeldt-Jakob Disease?

Which of the following is a potential risk factor for sporadic Creutzfeldt-Jakob Disease?

Which of the following is a characteristic histopathological finding in Creutzfeldt-Jakob Disease?

What is the estimated annual incidence rate of sporadic Creutzfeldt-Jakob Disease per million population?

Which region of the world has reported the highest incidence of variant Creutzfeldt-Jakob Disease cases?

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