#1
Which of the following is a characteristic feature of Prader-Willi Syndrome?
Excessive eating leading to obesity
ExplanationCharacteristic feature marked by insatiable hunger.
#2
What age range typically marks the onset of hyperphagia in individuals with Prader-Willi Syndrome?
Adolescence
ExplanationOnset of insatiable hunger often occurs during adolescence.
#3
Which parent-specific gene expression is affected in Prader-Willi Syndrome?
Paternally expressed genes are silenced
ExplanationAbnormal gene expression pattern involving the silencing of genes from the father.
#4
Which of the following is a common characteristic behavior observed in individuals with Prader-Willi Syndrome?
Excessive friendliness
ExplanationTendency to display unusually friendly behavior.
#5
Which of the following statements is true regarding Prader-Willi Syndrome and autism spectrum disorder?
Some individuals with Prader-Willi Syndrome may also have autism spectrum disorder.
ExplanationOverlap between Prader-Willi Syndrome and autism spectrum disorder in some cases.
#6
What genetic abnormality is associated with Prader-Willi Syndrome?
Deletion of chromosome 15
ExplanationGenetic basis involving a missing portion of chromosome 15.
#7
Which of the following is not a common symptom of Prader-Willi Syndrome?
Excessive sweating
ExplanationNot typically associated with Prader-Willi Syndrome.
#8
Which of the following medical conditions is often associated with Prader-Willi Syndrome?
Sleep apnea
ExplanationCommonly co-occurring condition affecting breathing during sleep.
#9
In Prader-Willi Syndrome, what is the role of the hypothalamus in relation to hunger and satiety?
Suppressed hunger signals
ExplanationHypothalamus fails to regulate hunger and satiety signals properly.
#10
What is the role of early intervention in managing Prader-Willi Syndrome?
It can improve cognitive function
ExplanationEarly intervention may lead to better cognitive outcomes.
#11
What is the prevalence of Prader-Willi Syndrome?
1 in 10,000 live births
ExplanationRelatively rare genetic disorder affecting approximately 1 in 10,000 live births.
#12
Which hormone deficiency is commonly observed in individuals with Prader-Willi Syndrome?
Growth hormone
ExplanationCommon hormonal imbalance leading to growth issues.
#13
Which therapy is often recommended for managing behavioral issues in individuals with Prader-Willi Syndrome?
Cognitive-behavioral therapy
ExplanationTherapeutic approach targeting behavioral patterns and cognitive restructuring.
#14
What is the life expectancy of individuals with Prader-Willi Syndrome?
Slightly reduced life expectancy
ExplanationLife expectancy is slightly lower compared to the general population.
#15
What is the primary cause of death in individuals with Prader-Willi Syndrome?
Complications from obesity
ExplanationObesity-related health issues are the leading cause of mortality.