#1
Which factor is deficient in hemophilia A?
Factor II
Factor VII
Factor VIII
Factor IX
#2
Which factor is deficient in hemophilia B?
Factor II
Factor VII
Factor VIII
Factor IX
#3
What is the primary goal of hemophilia treatment?
To normalize platelet count
To prevent joint damage
To maintain normal clotting factor levels
To reduce fibrinogen levels
#4
Which of the following is a characteristic feature of hemophilia?
Increased risk of thrombosis
Spontaneous joint hemorrhages
Prolonged PT and INR
Normal bleeding tendency
#5
What is the primary mode of inheritance for hemophilia?
Autosomal dominant
X-linked recessive
Autosomal recessive
Y-linked
#6
What is the most common form of treatment for hemophilia?
Anticoagulants
Thrombolytics
Factor replacement therapy
Platelet transfusion
#7
Which of the following is NOT a complication of hemophilia treatment?
Inhibitor development
Thrombosis
Joint damage
Intracranial hemorrhage
#8
Which type of hemophilia is also known as Christmas disease?
Hemophilia A
Hemophilia B
Hemophilia C
Hemophilia D
#9
Which of the following is a complication associated with long-term prophylactic treatment in hemophilia?
Decreased risk of joint damage
Increased risk of inhibitor development
Improved clotting factor levels
Reduced need for factor replacement therapy
#10
What is the role of cryoprecipitate in the management of hemophilia?
To increase platelet count
To provide clotting factor replacement
To prevent inhibitor development
To reduce fibrinogen levels
#11
What is the mechanism of action of recombinant factor VIII?
Inhibition of thrombin formation
Enhancement of platelet aggregation
Replacement of deficient factor
Induction of fibrinolysis
#12
Which of the following medications is commonly used for immune tolerance induction in patients with hemophilia?
Desmopressin
Emicizumab
Prothrombin complex concentrate
Rituximab
#13
What is the mechanism of action of emicizumab in the treatment of hemophilia?
Enhancement of factor VIII activity
Inhibition of factor IXa
Replacement of factor IX
Promotion of platelet aggregation
#14
Which of the following factors contributes to the development of inhibitors in patients with hemophilia?
Age of onset
Frequency of factor replacement therapy
Type of hemophilia
Genetic mutation
#15
What is the mechanism of action of desmopressin (DDAVP) in the treatment of hemophilia?
Enhancement of platelet aggregation
Release of von Willebrand factor
Replacement of factor VIII
Inhibition of fibrinolysis