#1
Which of the following is a major CYP inhibitor?
Cimetidine
ExplanationCimetidine is a major CYP inhibitor.
#2
Which CYP3A4 inhibitor is often used to boost the plasma levels of certain HIV protease inhibitors?
Ritonavir
ExplanationRitonavir is used to boost plasma levels of HIV protease inhibitors as a CYP3A4 inhibitor.
#3
Which CYP3A4 inhibitor is often used as a pharmacokinetic enhancer for certain protease inhibitors in HIV therapy?
Ritonavir
ExplanationRitonavir is often used as a pharmacokinetic enhancer for HIV therapy by boosting certain protease inhibitors as a CYP3A4 inhibitor.
#4
Which CYP3A4 inhibitor is often used to enhance the bioavailability of certain immunosuppressant drugs like tacrolimus?
Ritonavir
ExplanationRitonavir is often used to enhance the bioavailability of immunosuppressant drugs like tacrolimus as a CYP3A4 inhibitor.
#5
What is the mnemonic for remembering major CYP3A4 inhibitors?
GRAPEFRUIT
ExplanationThe mnemonic 'GRAPEFRUIT' helps remember major CYP3A4 inhibitors.
#6
Which drug is a strong CYP2D6 inhibitor?
Quinidine
ExplanationQuinidine is a strong CYP2D6 inhibitor.
#7
Which CYP inhibitor is commonly associated with the drug interaction known as the 'grapefruit juice effect'?
Verapamil
ExplanationVerapamil is commonly associated with the 'grapefruit juice effect' as a CYP inhibitor.
#8
What is the mnemonic for remembering major CYP3A4 inducers?
RUGRAT INDUCERS
ExplanationThe mnemonic 'RUGRAT INDUCERS' helps remember major CYP3A4 inducers.
#9
Which CYP inhibitor is known for its interaction with statins, increasing the risk of myopathy?
Erythromycin
ExplanationErythromycin is a CYP inhibitor associated with statin interactions and myopathy risk.
#10
In the mnemonic 'G-PACMAN,' what does 'G' represent regarding CYP inhibition?
Gemfibrozil
Explanation'G' in 'G-PACMAN' stands for Gemfibrozil in CYP inhibition.
#11
Which CYP inhibitor is known to cause a potential drug interaction with warfarin, leading to an increased risk of bleeding?
Fluconazole
ExplanationFluconazole is a CYP inhibitor associated with increased bleeding risk when interacting with warfarin.
#12
In the mnemonic 'SSWIFT GEMS,' what does 'S' represent regarding CYP inhibition?
St. John's Wort
Explanation'S' in 'SSWIFT GEMS' represents St. John's Wort in CYP inhibition.