#1
Which vitamin is essential for the synthesis of clotting factors?
Vitamin K
ExplanationVitamin K is necessary for the synthesis of clotting factors.
#2
Which of the following is NOT a component of hemostasis?
Erythropoiesis
ExplanationErythropoiesis is not part of hemostasis; it's the production of red blood cells.
#3
Which of the following is a congenital bleeding disorder characterized by a deficiency or dysfunction of von Willebrand factor?
von Willebrand disease
Explanationvon Willebrand disease is characterized by von Willebrand factor deficiency or dysfunction.
#4
What is the physiological function of antithrombin III in blood clotting?
Inhibiting coagulation factors
ExplanationAntithrombin III inhibits coagulation factors to prevent clot formation.
#5
Which protein is responsible for the formation of the stable fibrin clot in blood coagulation?
Fibrin
ExplanationFibrin is responsible for forming stable clots in blood coagulation.
#6
What is the term for the process of breaking down a blood clot?
Fibrinolysis
ExplanationFibrinolysis is the process of breaking down blood clots.
#7
Which enzyme converts fibrinogen into fibrin during blood clotting?
Thrombin
ExplanationThrombin converts fibrinogen into fibrin during clotting.
#8
Which of the following clotting factors is NOT vitamin K-dependent?
Factor VIII
ExplanationFactor VIII is not dependent on Vitamin K for its function.
#9
Which of the following is a characteristic feature of disseminated intravascular coagulation (DIC)?
Excessive clotting
ExplanationDIC is characterized by excessive clotting.
#10
What is the mechanism of action of heparin in preventing blood clotting?
Inhibiting thrombin activity
ExplanationHeparin prevents blood clotting by inhibiting thrombin activity.
#11
Which coagulation factor is activated by the intrinsic pathway of blood coagulation?
Factor XII
ExplanationFactor XII is activated by the intrinsic pathway of blood coagulation.
#12
Which of the following is a drug commonly used to prevent the formation of blood clots?
Warfarin
ExplanationWarfarin is commonly used to prevent blood clot formation.
#13
What is the primary function of von Willebrand factor (vWF) in hemostasis?
Platelet activation
Explanationvon Willebrand factor primarily activates platelets in hemostasis.
#14
Which of the following conditions is characterized by the formation of abnormal blood clots in small blood vessels throughout the body?
Thrombotic thrombocytopenic purpura
ExplanationThrombotic thrombocytopenic purpura is characterized by abnormal clot formation in small blood vessels.
#15
What is the primary role of tissue plasminogen activator (tPA) in the process of hemostasis?
Activating fibrinolysis
ExplanationtPA primarily activates fibrinolysis in hemostasis.
#16
Which of the following conditions is characterized by a deficiency in ADAMTS13, leading to the formation of microthrombi in small blood vessels?
Thrombotic thrombocytopenic purpura
ExplanationThrombotic thrombocytopenic purpura results from ADAMTS13 deficiency, leading to microthrombi formation.
#17
What is the primary function of the intrinsic pathway of blood coagulation?
Formation of thrombin
ExplanationThe primary function of the intrinsic pathway is the formation of thrombin in blood coagulation.