#1
Which of the following conditions is commonly treated with glucocorticoids?
Hyperthyroidism
Rheumatoid arthritis
Hypertension
Type 2 diabetes
#2
Which of the following is a synthetic glucocorticoid commonly used in the treatment of inflammatory conditions?
Cortisone
Hydrocortisone
Methylprednisolone
Prednisolone
#3
Which of the following is a common adverse effect of short-term glucocorticoid use?
Cushing's syndrome
Hypoglycemia
Hypotension
Hyperkalemia
#4
Which laboratory parameter is likely to be affected by long-term glucocorticoid therapy?
Serum potassium levels
Hemoglobin concentration
Platelet count
Serum sodium levels
#5
Which of the following is a common topical glucocorticoid used for skin inflammation?
Prednisolone
Dexamethasone
Hydrocortisone
Methylprednisolone
#6
Which of the following is a common adverse effect of short-term glucocorticoid use in children?
Growth retardation
Hyperactivity
Hypoglycemia
Hypertension
#7
What is the primary mechanism of action of glucocorticoids?
Blocking histamine receptors
Inhibiting prostaglandin synthesis
Suppressing the immune response
Increasing insulin production
#8
Which organ is primarily responsible for the metabolism of glucocorticoids?
#9
Which glucocorticoid is known for its high anti-inflammatory potency?
Prednisone
Dexamethasone
Cortisone
Hydrocortisone
#10
How do glucocorticoids exert their anti-inflammatory effects?
Stabilizing lysosomal membranes
Increasing mast cell degranulation
Enhancing neutrophil activity
Blocking COX-2 enzyme
#11
In glucocorticoid therapy, what is the purpose of tapering the dose during discontinuation?
To prevent rebound inflammation
To increase the therapeutic effect
To minimize drug interactions
To reduce side effects
#12
What is the role of glucocorticoids in the stress response?
Enhancing memory formation
Promoting vasoconstriction
Suppressing the immune system
Increasing insulin release
#13
What is the role of glucocorticoids in metabolism?
Stimulating appetite
Increasing glycogen synthesis
Promoting gluconeogenesis
Enhancing insulin sensitivity
#14
What is the main side effect associated with long-term use of glucocorticoids?
Hypertension
Hyperkalemia
Osteoporosis
Hypoglycemia
#15
In the context of glucocorticoids, what does the term 'half-life' refer to?
Time taken for complete elimination from the body
Time taken for onset of action
Time taken for peak plasma concentration
Time taken for metabolism in the liver
#16
What is the primary mineralocorticoid produced by the adrenal cortex?
Cortisol
Aldosterone
Progesterone
DHEA
#17
Which physiological process is negatively regulated by glucocorticoids?
Glycogenolysis
Protein synthesis
Lipolysis
Inflammation
#18
Which receptor mediates the genomic effects of glucocorticoids?
Alpha-adrenergic receptor
Beta-adrenergic receptor
Mineralocorticoid receptor
Glucocorticoid receptor