#1
What is the primary genetic mutation associated with cystic fibrosis?
CFTR
ExplanationCFTR mutation causes cystic fibrosis.
#2
Which of the following organs is primarily affected by cystic fibrosis?
Lungs
ExplanationLungs are primarily affected due to mucus buildup.
#3
Which of the following organs is affected by the defective CFTR protein in cystic fibrosis?
Pancreas
ExplanationPancreas is affected due to mucus blockage.
#4
What is the primary cause of respiratory failure in cystic fibrosis patients?
Bronchiectasis
ExplanationBronchiectasis leads to respiratory failure.
#5
Which of the following best describes the pathophysiology of cystic fibrosis?
Increased mucus production causing airway obstruction
ExplanationExcessive mucus production obstructs airways.
#6
Which of the following clinical manifestations is NOT commonly associated with cystic fibrosis?
Hypertension
ExplanationHypertension is not commonly associated.
#7
Which of the following is a characteristic feature of cystic fibrosis on chest radiography?
Hyperinflation
ExplanationHyperinflation is commonly seen.
#8
What is the primary mechanism leading to pancreatic insufficiency in cystic fibrosis?
Obstruction of pancreatic ducts
ExplanationDuct obstruction causes insufficiency.
#9
What is the gold standard diagnostic test for cystic fibrosis?
Sweat chloride test
ExplanationSweat chloride test is highly accurate.
#10
Which of the following is a common symptom of cystic fibrosis in newborns?
Jaundice
ExplanationJaundice can occur due to liver involvement.
#11
What is the primary cause of male infertility in individuals with cystic fibrosis?
Absent vas deferens
ExplanationAbsence of vas deferens causes infertility.
#12
Which of the following is a potential cause of distal intestinal obstruction syndrome (DIOS) in individuals with cystic fibrosis?
Mucus impaction
ExplanationDIOS can occur due to mucus blockage.