#1
Which organ is primarily affected by cystic fibrosis?
Lungs
ExplanationCystic fibrosis primarily affects the lungs, causing mucus buildup and breathing difficulties.
#2
What is the main cause of cystic fibrosis?
Genetic mutation
ExplanationCystic fibrosis is primarily caused by a genetic mutation affecting the CFTR gene.
#3
Which of the following is NOT a common symptom of cystic fibrosis?
Skin rash
ExplanationSkin rash is not a common symptom of cystic fibrosis; it primarily affects the lungs and digestive system.
#4
What is the average life expectancy for individuals with cystic fibrosis?
40-50 years
ExplanationThe average life expectancy for individuals with cystic fibrosis is around 40 to 50 years, though it varies.
#5
What is the gold standard diagnostic test for cystic fibrosis?
Sweat test
ExplanationThe sweat test is the gold standard diagnostic test for cystic fibrosis, measuring the concentration of salt in sweat.
#6
Which of the following is a common respiratory complication of cystic fibrosis?
Chronic bronchitis
ExplanationChronic bronchitis is a common respiratory complication of cystic fibrosis, leading to inflammation and mucus buildup in the airways.
#7
What is the primary treatment goal for individuals with cystic fibrosis?
Disease modification
ExplanationThe primary treatment goal for cystic fibrosis is disease modification, aiming to slow disease progression and improve quality of life.
#8
Which complication of cystic fibrosis involves the abnormal accumulation of thick mucus in the intestines?
Meconium ileus
ExplanationMeconium ileus is a complication of cystic fibrosis characterized by thick mucus blockage in the intestines, usually seen in newborns.
#9
Which genetic mutation is most commonly associated with cystic fibrosis?
F508del
ExplanationThe F508del mutation is the most common genetic mutation associated with cystic fibrosis, affecting the CFTR protein.
#10
Which of the following is NOT a potential complication of cystic fibrosis-related diabetes (CFRD)?
Hypothyroidism
ExplanationHypothyroidism is not a common complication of cystic fibrosis-related diabetes; CFRD primarily affects glucose metabolism.
#11
What is the primary cause of male infertility in individuals with cystic fibrosis?
Obstruction of the vas deferens
ExplanationMale infertility in cystic fibrosis is primarily due to the obstruction of the vas deferens, preventing sperm from reaching the ejaculate.
#12
Which of the following is a potential complication of long-term antibiotic therapy in cystic fibrosis patients?
Osteoporosis
ExplanationOsteoporosis is a potential complication of long-term antibiotic therapy in cystic fibrosis patients, due to its impact on bone health.