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Cellular Adaptations and Pathological Changes Quiz

#1

Which of the following cellular adaptations involves an increase in cell size?

Hypertrophy
Explanation

Enlargement of individual cells without cell division.

#2

Which type of cellular adaptation is typically seen in response to prolonged stress or hormonal stimulation?

Hyperplasia
Explanation

Increase in the number of cells in an organ or tissue.

#3

Which of the following is a characteristic feature of apoptosis?

Cell shrinkage
Explanation

Programmed cell death involving cell shrinkage and fragmentation.

#4

Which type of cellular injury is caused by an insufficient oxygen supply to tissues?

Ischemic injury
Explanation

Tissue damage due to inadequate blood supply.

#5

Which type of necrosis is typically seen in the brain following ischemic injury?

Liquefactive necrosis
Explanation

Rapid dissolution of dead cells, creating a liquid mass.

#6

What is the term for programmed cell death that occurs in multicellular organisms?

Apoptosis
Explanation

Regulated and orderly cell death.

#7

Which type of necrosis is commonly observed in immune-mediated vasculitis?

Fibrinoid necrosis
Explanation

Deposition of fibrin-like proteinaceous material in vessel walls.

#8

Which of the following is a reversible cellular injury?

Swelling
Explanation

Accumulation of water in cells causing them to swell.

#9

What is the term for abnormal changes in size, shape, and organization of cells?

Dysplasia
Explanation

Abnormal growth or development of cells.

#10

Which of the following is NOT a hallmark of reversible cell injury?

Mitochondrial dysfunction
Explanation

Impaired cellular energy production is a hallmark of irreversible injury.

#11

Which type of necrosis is typically associated with tuberculosis infections?

Caseous necrosis
Explanation

Dead cells persist as a soft, cheese-like debris.

#12

Which of the following is a characteristic feature of coagulative necrosis?

Preservation of tissue architecture
Explanation

Dead tissue maintains its structure for a time.

#13

Which type of necrosis is typically seen in the pancreas following acute pancreatitis?

Fat necrosis
Explanation

Enzymatic destruction of fat, resulting in inflammation.

#14

Which of the following is characteristic of necrosis?

Pathological process
Explanation

Death of cells in living tissue.

#15

Which of the following is an example of metaplasia?

Change of columnar epithelium to stratified squamous epithelium in the respiratory tract
Explanation

Replacement of one differentiated cell type with another.

#16

Which of the following is a characteristic feature of dystrophic calcification?

Calcium deposits in necrotic tissues
Explanation

Abnormal deposition of calcium salts in injured tissues.

#17

Which of the following cellular adaptations is considered a preneoplastic change?

Dysplasia
Explanation

Abnormal cell growth that may precede cancer development.

#18

Which of the following is a characteristic feature of metaplasia?

Replacement of one differentiated cell type with another
Explanation

Transformation of one cell type into another, typically in response to injury or stress.

#19

Which of the following cellular adaptations is considered a precursor to cancer?

Dysplasia
Explanation

Abnormal cell growth that may progress to cancer.

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