#1
Which class of drugs is commonly used as first-line therapy for hypertension?
Diuretics
ExplanationDiuretics are commonly used as first-line therapy for hypertension, promoting diuresis and reducing blood volume and pressure.
#2
What is the mechanism of action of aspirin as a cardiovascular medication?
Inhibition of cyclooxygenase (COX) enzymes
ExplanationAspirin acts by inhibiting cyclooxygenase (COX) enzymes, thereby preventing the formation of pro-inflammatory prostaglandins and reducing platelet aggregation.
#3
Which of the following drugs is a direct thrombin inhibitor used as an anticoagulant?
Dabigatran
ExplanationDabigatran is a direct thrombin inhibitor that functions as an anticoagulant by specifically targeting and inhibiting thrombin.
#4
What is the primary mechanism of action of statins in lowering cholesterol levels?
Inhibition of HMG-CoA reductase
ExplanationStatins lower cholesterol levels by inhibiting HMG-CoA reductase, a key enzyme in the synthesis of cholesterol in the liver.
#5
Which antiarrhythmic medication works by blocking sodium channels and is commonly used to treat ventricular arrhythmias?
Amiodarone
ExplanationAmiodarone, an antiarrhythmic medication, exerts its effects by blocking sodium channels and is commonly used in the treatment of ventricular arrhythmias.
#6
What is the primary mechanism of action of angiotensin II receptor blockers (ARBs) in cardiovascular therapy?
Blockade of angiotensin II receptors
ExplanationARBs work by blocking angiotensin II receptors, leading to vasodilation and reduced secretion of aldosterone, contributing to their cardiovascular therapeutic effects.
#7
Which of the following drugs is a phosphodiesterase inhibitor primarily used for the treatment of erectile dysfunction but may also be used for pulmonary arterial hypertension?
Sildenafil
ExplanationSildenafil, a phosphodiesterase inhibitor, is primarily used for erectile dysfunction and can also be employed in the treatment of pulmonary arterial hypertension.
#8
Which of the following drugs is a selective alpha-1 blocker used primarily for the treatment of benign prostatic hyperplasia (BPH) but may also be used for hypertension?
Prazosin
ExplanationPrazosin, a selective alpha-1 blocker, is primarily used for benign prostatic hyperplasia (BPH) and may also be used to manage hypertension.
#9
Which of the following drugs is a direct vasodilator used in the management of hypertensive emergencies?
Hydralazine
ExplanationHydralazine is a direct vasodilator used in the management of hypertensive emergencies, causing relaxation of smooth muscle in blood vessels.
#10
Which of the following medications is a direct renin inhibitor used for the treatment of hypertension?
Aliskiren
ExplanationAliskiren is a direct renin inhibitor used in the treatment of hypertension by blocking the renin-angiotensin-aldosterone pathway.
#11
What is the primary mechanism of action of digoxin in the treatment of heart failure?
Inhibition of sodium-potassium ATPase
ExplanationDigoxin treats heart failure by inhibiting sodium-potassium ATPase, leading to increased cardiac contractility and reduced heart rate.
#12
Which of the following medications is a potassium-sparing diuretic that antagonizes aldosterone receptors?
Spironolactone
ExplanationSpironolactone is a potassium-sparing diuretic that antagonizes aldosterone receptors, promoting diuresis without potassium loss.
#13
Which antiarrhythmic medication is known for prolonging the QT interval and is primarily used for treating ventricular arrhythmias?
Amiodarone
ExplanationAmiodarone, a potent antiarrhythmic, is known for prolonging the QT interval and is primarily used in treating ventricular arrhythmias.