#1
Which of the following is a primary phase of wound healing?
Inflammatory phase
ExplanationInitiates the healing process, involves inflammation, and removal of debris.
#2
Which of the following is NOT a factor that affects wound healing?
Exercise
ExplanationContrary to popular belief, moderate exercise generally supports wound healing.
#3
Which of the following is NOT a component of the extracellular matrix involved in wound healing?
Elon
ExplanationNot a component; extracellular matrix comprises various proteins and structural molecules.
#4
Which of the following cell types is responsible for phagocytosis of debris and bacteria during wound healing?
Macrophage
ExplanationEngulf debris and pathogens, crucial for cleaning the wound site and promoting healing.
#5
Which of the following is NOT a characteristic of chronic wounds?
High levels of growth factors
ExplanationChronic wounds often exhibit reduced levels of growth factors, hampering the healing process.
#6
Which cell type is primarily responsible for the production of collagen during wound healing?
Fibroblast
ExplanationSynthesizes and secretes collagen, essential for tissue repair and scar formation.
#7
Which growth factor plays a crucial role in stimulating angiogenesis during wound healing?
Vascular endothelial growth factor (VEGF)
ExplanationPromotes the formation of new blood vessels, crucial for oxygen and nutrient supply.
#8
Which type of collagen is predominant in mature scar tissue?
Type I collagen
ExplanationMain component of mature scars, provides strength and stability to the tissue.
#9
Which vitamin is essential for collagen synthesis and wound healing?
Vitamin C
ExplanationCritical for collagen formation, antioxidant properties aid tissue repair.
#10
Which of the following is a characteristic feature of chronic wounds?
High levels of inflammatory cytokines
ExplanationPersistent inflammation is a hallmark of chronic wounds, hindering the healing process.
#11
Which enzyme is involved in the breakdown of fibrin during wound healing?
Plasmin
ExplanationCleaves fibrin, helps in clot removal, and prepares the wound for tissue repair.
#12
Which growth factor is involved in the regulation of cell migration during wound healing?
Platelet-derived growth factor (PDGF)
ExplanationStimulates cell migration, particularly fibroblasts, essential for tissue repair.
#13
Which type of wound dressing promotes a moist wound environment and facilitates autolytic debridement?
Hydrocolloid dressings
ExplanationMaintains moisture, aids in autolytic debridement, and supports a conducive healing environment.
#14
Which enzyme is responsible for cross-linking collagen molecules during wound healing?
Lysyl oxidase
ExplanationForms stable cross-links between collagen molecules, providing strength to the healing tissue.
#15
Which enzyme is responsible for the breakdown of extracellular matrix components during tissue remodeling?
Matrix metalloproteinase (MMP)
ExplanationFacilitates tissue remodeling by degrading old or damaged extracellular matrix components.