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Toxicology and Poisoning Quiz

#1

Which of the following is not a route of exposure to toxic substances?

Exhalation
Explanation

Exhalation is not a route of exposure; inhalation, ingestion, and dermal contact are common routes.

#2

Which of the following is considered a heavy metal poison?

Arsenic
Explanation

Arsenic is a heavy metal poison known to cause various health issues including cancer.

#3

Which of the following organs is primarily affected by carbon monoxide poisoning?

Brain
Explanation

Carbon monoxide primarily affects the brain by binding to hemoglobin, reducing oxygen delivery.

#4

What is the antidote for cyanide poisoning?

Sodium thiosulfate
Explanation

Sodium thiosulfate acts as an antidote by converting cyanide to thiocyanate, which is less toxic.

#5

Which of the following substances can cause methemoglobinemia?

Nitrites
Explanation

Nitrites cause methemoglobinemia by oxidizing hemoglobin to its ferric form, impairing oxygen transport.

#6

What is the main toxic component in snake venom?

Protein
Explanation

Proteins, including enzymes and toxins, are the main toxic components in snake venom.

#7

What is the antidote for acetaminophen (paracetamol) poisoning?

N-acetylcysteine
Explanation

N-acetylcysteine is the antidote for acetaminophen overdose, acting to replenish depleted glutathione levels.

#8

Which of the following is a characteristic feature of organophosphate poisoning?

Muscle fasciculations
Explanation

Muscle fasciculations are common in organophosphate poisoning due to excessive acetylcholine stimulation.

#9

Which of the following is a common symptom of lead poisoning in children?

Hyperactivity
Explanation

Hyperactivity is a common symptom of lead poisoning in children, along with other neurocognitive effects.

#10

What is the primary mechanism of action of nerve agents such as sarin?

Inhibition of acetylcholinesterase
Explanation

Nerve agents like sarin inhibit acetylcholinesterase, leading to excessive acetylcholine accumulation.

#11

What is the antidote for anticholinergic poisoning?

Physostigmine
Explanation

Physostigmine, a reversible cholinesterase inhibitor, is used to treat anticholinergic toxicity.

#12

Which of the following is a characteristic feature of mercury poisoning?

Peripheral neuropathy
Explanation

Peripheral neuropathy is a common neurological manifestation of chronic mercury exposure.

#13

Which of the following is an example of a plant-derived poison?

Ricin
Explanation

Ricin is a highly toxic protein derived from the castor bean plant.

#14

Which of the following is a characteristic feature of mushroom poisoning?

Liver failure
Explanation

Liver failure is a characteristic feature of mushroom poisoning due to hepatotoxic compounds.

#15

What is the primary toxic effect of ethylene glycol ingestion?

Nephrotoxicity
Explanation

Ethylene glycol ingestion leads to nephrotoxicity and metabolic acidosis due to its metabolites.

#16

Which of the following is a characteristic feature of antifreeze poisoning?

Metabolic acidosis
Explanation

Metabolic acidosis is a common feature of antifreeze poisoning, caused by its metabolite, oxalic acid.

#17

Which of the following is a characteristic feature of ricin poisoning?

Gastrointestinal symptoms
Explanation

Ricin poisoning typically presents with severe gastrointestinal symptoms due to its toxicity.

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