Microbial Metabolism and Enzymology Quiz

Pyruvate kinase catalyzes the final step of glycolysis, converting phosphoenolpyruvate to pyruvate.

NAD+ is a coenzyme derived from niacin and plays a crucial role in redox reactions.

Glycolysis can occur anaerobically, independent of oxygen availability.

DNA polymerase I plays a major role in DNA replication in bacteria, particularly in removing RNA primers and filling the gaps.

The Krebs cycle, also known as the citric acid cycle, occurs in the mitochondrial matrix and plays a central role in cellular respiration.

ATP synthesis in glycolysis primarily occurs through substrate-level phosphorylation.

RNA polymerase catalyzes the transcription process, synthesizing mRNA from a DNA template.

The electron transport chain primarily occurs in the cell membrane of bacteria, where ATP is synthesized.

Non-competitive inhibitors bind to a site on the enzyme other than the active site, altering the enzyme's conformation and reducing its activity.

Ribose-5-phosphate is a key product of the pentose phosphate pathway, which serves as a precursor for nucleotide synthesis.

Competitive inhibitors bind to the active site of the enzyme, competing with the substrate for binding.

Allosteric enzymes have activity regulated by the binding of effectors at sites other than the active site, which can enhance or inhibit enzyme activity.

Irreversible inhibitors covalently bind to the enzyme, leading to permanent inactivation.

Ribonucleotide reductase is involved in DNA synthesis, converting ribonucleotides to deoxyribonucleotides, a crucial step in DNA replication and repair.