#1
Which of the following is a major extracellular cation?
Sodium (Na+)
ExplanationSodium is the primary extracellular cation responsible for maintaining osmotic balance and regulating water distribution in the body.
#2
Which electrolyte is primarily responsible for maintaining resting membrane potential in cells?
Potassium (K+)
ExplanationPotassium is the main intracellular cation responsible for establishing and maintaining the resting membrane potential in cells.
#3
Which type of immunity is mediated by T lymphocytes?
Cell-mediated immunity
ExplanationCell-mediated immunity is a type of immune response mediated by T lymphocytes, which directly target and destroy infected or abnormal cells.
#4
Which of the following cells are responsible for antibody production?
Lymphocytes
ExplanationLymphocytes, particularly B lymphocytes (B cells), are primarily responsible for antibody production as part of the adaptive immune response.
#5
Which type of immunity is conferred through the transfer of antibodies from one individual to another?
Passive immunity
ExplanationPassive immunity is acquired through the transfer of pre-formed antibodies from one individual to another, providing immediate but temporary protection against specific pathogens or toxins.
#6
What is the normal serum sodium concentration in the human body?
135-145 mmol/L
ExplanationThe normal serum sodium concentration in the human body typically ranges from 135 to 145 millimoles per liter (mmol/L).
#7
Which electrolyte imbalance can lead to muscle weakness, cardiac arrhythmias, and neurological symptoms such as seizures?
Hypokalemia
ExplanationHypokalemia, or low potassium levels, can cause muscle weakness, cardiac arrhythmias, and neurological symptoms like seizures due to disruptions in nerve and muscle function.
#8
Which of the following electrolyte imbalances is associated with prolonged QT interval on an electrocardiogram (ECG)?
Hypokalemia
ExplanationHypokalemia, or low potassium levels, can lead to prolongation of the QT interval on an electrocardiogram (ECG), which may predispose individuals to cardiac arrhythmias.
#9
Which hormone plays a crucial role in regulating serum calcium levels?
Parathyroid hormone
ExplanationParathyroid hormone (PTH) is essential for regulating serum calcium levels by increasing calcium reabsorption from the bones and kidneys and promoting calcium absorption in the intestines.
#10
Which electrolyte imbalance is commonly seen in patients with chronic renal failure?
Hyperphosphatemia
ExplanationHyperphosphatemia, or elevated phosphate levels, is commonly observed in patients with chronic renal failure due to impaired phosphate excretion by the kidneys.
#11
Which of the following is NOT a symptom of hypercalcemia?
Tetany
ExplanationTetany, or involuntary muscle spasms, is not typically associated with hypercalcemia; instead, it is more commonly observed in hypocalcemia, which is low calcium levels.
#12
Which of the following conditions is characterized by a deficiency of circulating granulocytes and monocytes?
Neutropenia
ExplanationNeutropenia is a condition characterized by a decreased number of circulating neutrophils, a type of white blood cell important for fighting infections.
#13
What is the primary cellular target of aldosterone?
Renal tubules
ExplanationAldosterone primarily acts on the renal tubules in the kidneys to regulate electrolyte balance, particularly sodium and potassium, and control blood pressure.
#14
Which of the following hormones is responsible for stimulating bone resorption and increasing serum calcium levels?
Parathyroid hormone
ExplanationParathyroid hormone (PTH) stimulates bone resorption, releasing calcium into the bloodstream, and enhances calcium reabsorption in the kidneys, thereby increasing serum calcium levels.
#15
Which type of T cells are responsible for suppressing excessive immune responses and preventing autoimmune reactions?
Regulatory T cells
ExplanationRegulatory T cells, also known as suppressor T cells, play a crucial role in suppressing excessive immune responses and preventing autoimmune reactions by modulating the activity of other immune cells.
#16
Which electrolyte imbalance can lead to cardiac dysrhythmias and ECG changes such as peaked T waves?
Hyperkalemia
ExplanationHyperkalemia, or elevated potassium levels, can lead to cardiac dysrhythmias and electrocardiogram (ECG) changes such as peaked T waves, which may progress to more severe arrhythmias and cardiac arrest.