#1
Which neurotransmitter is commonly associated with pain perception?
Endorphins
ExplanationEndorphins are natural pain relievers produced by the body in response to stress and pain.
#2
What is the most common type of chronic pain?
Low back pain
ExplanationLow back pain is a prevalent type of chronic pain affecting millions worldwide.
#3
Which of the following is a non-pharmacological approach to pain management?
Acupuncture
ExplanationAcupuncture involves inserting thin needles into specific points on the body to alleviate pain by stimulating nerves and releasing endorphins.
#4
What is the first-line treatment for acute pain?
Nonsteroidal anti-inflammatory drugs (NSAIDs)
ExplanationNSAIDs are commonly recommended as first-line treatment for acute pain due to their anti-inflammatory and analgesic properties.
#5
Which of the following medications is often used to manage neuropathic pain?
Gabapentin
ExplanationGabapentin is commonly prescribed for neuropathic pain as it blocks calcium channels, reducing abnormal pain signals.
#6
What psychological therapy technique is frequently employed in pain management?
Cognitive-behavioral therapy (CBT)
ExplanationCBT helps patients manage pain by identifying and changing negative thoughts and behaviors.
#7
Which of the following is NOT a potential complication of long-term opioid use?
Hypotension
ExplanationHypotension (low blood pressure) is not typically associated with long-term opioid use, unlike constipation, respiratory depression, and addiction.
#8
What is the primary goal of multimodal analgesia?
To achieve better pain control with fewer side effects
ExplanationMultimodal analgesia combines different medications and techniques to target pain from multiple angles, improving efficacy and reducing side effects.
#9
Which of the following is a characteristic feature of neuropathic pain?
Pain is often accompanied by abnormal sensations like burning or tingling
ExplanationNeuropathic pain arises from nerve damage or dysfunction and is often described as burning, shooting, or tingling.
#10
Which of the following is a potential side effect of opioid therapy?
Constipation
ExplanationConstipation is a common side effect of opioid therapy due to decreased gastrointestinal motility.
#11
Which region of the brain is heavily involved in the perception of pain?
Thalamus
ExplanationThe thalamus is a key relay center for sensory information, including pain signals, in the brain.
#12
What is the mechanism of action of NSAIDs in pain management?
Inhibiting COX enzymes
ExplanationNSAIDs work by inhibiting cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause pain and inflammation.
#13
What is the role of the sympathetic nervous system in pain perception?
It amplifies pain signals
ExplanationThe sympathetic nervous system can amplify pain signals, contributing to the perception of pain.
#14
Which neurotransmitter is involved in the descending modulation of pain signals?
Serotonin
ExplanationSerotonin plays a role in the descending modulation of pain signals, helping to inhibit pain transmission in the spinal cord.
#15
What is the primary effect of corticosteroids in pain management?
Pain relief by inhibiting prostaglandin synthesis
ExplanationCorticosteroids reduce inflammation and pain by inhibiting the synthesis of prostaglandins.
#16
What is the primary mechanism of action of gabapentin in pain management?
Blocking calcium channels
ExplanationGabapentin reduces pain by blocking calcium channels in the nervous system, thereby inhibiting the transmission of pain signals.