#1
Which of the following is a common side effect of chemotherapy?
Nausea and vomiting
ExplanationCommon gastrointestinal side effects.
#2
Which route of administration is commonly used for chemotherapy drugs?
Intravenous
ExplanationDirect delivery into the bloodstream.
#3
Which drug is commonly used in chemotherapy to inhibit DNA synthesis?
Fluorouracil
ExplanationInhibits thymidylate synthase.
#4
What is the purpose of combination chemotherapy?
To target cancer cells at different stages of the cell cycle
ExplanationEnhanced efficacy by targeting multiple pathways.
#5
What is the purpose of premedication before chemotherapy?
To prevent allergic reactions and reduce side effects
ExplanationMinimizing adverse reactions.
#6
Which of the following is a common chemotherapy regimen for breast cancer?
AC-T
ExplanationCombination therapy with doxorubicin and cyclophosphamide.
#7
Which chemotherapy drug is associated with the side effect of peripheral neuropathy?
Vincristine
ExplanationDamages peripheral nerves.
#8
What is the mechanism of action of alkylating agents in chemotherapy?
Cross-link DNA strands
ExplanationForms covalent bonds within DNA.
#9
What is the purpose of dose intensity in chemotherapy?
To maintain therapeutic efficacy by administering drugs at optimal intervals
ExplanationSustaining effective drug levels.
#10
What is the primary goal of neoadjuvant chemotherapy?
To improve surgical outcomes by shrinking tumors before surgery
ExplanationReduces tumor size prior to surgery.
#11
What is the mechanism of action of antimetabolites in chemotherapy?
Inhibit DNA synthesis by mimicking nucleotides
ExplanationInterferes with nucleotide metabolism.
#12
What is the purpose of hematopoietic growth factors in chemotherapy?
To enhance the production of red and white blood cells
ExplanationPrevents or treats myelosuppression.