#1
Which of the following is a major risk factor for developing atherosclerosis?
High blood pressure
ExplanationHigh blood pressure increases stress on arterial walls, promoting atherosclerosis.
#2
Which of the following imaging modalities is commonly used to diagnose atherosclerosis?
Angiography
ExplanationAngiography is a common imaging technique for visualizing blood vessels and detecting atherosclerotic lesions.
#3
What is the main source of cholesterol in the human body?
Liver synthesis
ExplanationThe liver synthesizes cholesterol, serving as the primary source of cholesterol in the human body.
#4
Which of the following dietary components is associated with increased risk of atherosclerosis?
Trans fats
ExplanationConsuming trans fats is associated with an increased risk of atherosclerosis and cardiovascular diseases.
#5
Which of the following is a non-modifiable risk factor for atherosclerosis?
Age
ExplanationAge is a non-modifiable risk factor for atherosclerosis, with risk increasing as individuals age.
#6
What is the primary pathological process involved in atherosclerosis?
Accumulation of plaque in arteries
ExplanationAtherosclerosis is characterized by the buildup of plaque, mainly composed of cholesterol, in arterial walls.
#7
Which lipoprotein is commonly referred to as 'bad cholesterol'?
LDL
ExplanationLDL (Low-Density Lipoprotein) is considered 'bad cholesterol' due to its role in depositing cholesterol in arteries.
#8
What is the most common cause of death in individuals with atherosclerosis?
Heart attack
ExplanationAtherosclerosis can lead to the formation of blood clots, causing heart attacks, a common fatal consequence.
#9
Which of the following is NOT a potential complication of atherosclerosis?
Atrial fibrillation
ExplanationAtrial fibrillation is not a direct complication of atherosclerosis; it's a separate heart rhythm disorder.
#10
What is the recommended target for LDL cholesterol levels in individuals at high risk for atherosclerotic cardiovascular disease?
Less than 100 mg/dL
ExplanationMaintaining LDL cholesterol levels below 100 mg/dL is recommended for high-risk individuals to prevent atherosclerotic events.
#11
Which of the following medications is commonly used for secondary prevention of cardiovascular events in patients with atherosclerosis?
Beta-blockers
ExplanationBeta-blockers are commonly prescribed for secondary prevention of cardiovascular events in individuals with atherosclerosis.
#12
Which of the following lifestyle changes can help prevent atherosclerosis?
Maintaining a healthy weight
ExplanationMaintaining a healthy weight reduces the risk of atherosclerosis by managing key cardiovascular risk factors.
#13
What is the role of endothelial dysfunction in the development of atherosclerosis?
It allows for the accumulation of lipids in the arterial wall
ExplanationEndothelial dysfunction enables lipids to accumulate in arterial walls, contributing to atherosclerosis.
#14
What is the primary mechanism by which statins reduce the risk of cardiovascular events in patients with atherosclerosis?
Lowering LDL cholesterol levels
ExplanationStatins lower LDL cholesterol levels, reducing the risk of atherosclerosis-related cardiovascular events.
#15
What is the term for the process by which atherosclerotic plaques rupture, leading to thrombus formation and acute occlusion of the vessel?
Thrombosis
ExplanationThrombosis is the process where ruptured plaques lead to blood clot formation and sudden vessel blockage in atherosclerosis.
#16
What is the role of smooth muscle cells in the progression of atherosclerosis?
They secrete collagen to stabilize plaques
ExplanationSmooth muscle cells play a role in stabilizing atherosclerotic plaques by secreting collagen.
#17
What role do macrophages play in the development of atherosclerosis?
They phagocytose lipids and become foam cells
ExplanationMacrophages phagocytose lipids in arterial walls, transforming into foam cells and contributing to atherosclerosis.